Secure production multi-agent systems using Azure zero-trust architecture principles. Apply per-agent managed identities with least-privilege access and design authentication flows covering managed identity, on-behalf-of (OBO), user-delegated, and key-based patterns. Manage secrets lifecycle with Azure Key Vault, including rotation and customer-managed keys (CMK) encryption, and design network controls to prevent lateral movement. Implement multitenant data isolation and configure compliance controls for enterprise regulatory requirements.